Research looked at prevalence of chronic traumatic encephalopathy in 2,362 players who died in 2008-2023

A new study published on Wednesday estimates that about 75% of former NFL players who died over a 15-year period had evidence of chronic traumatic encephalopathy (CTE).

The research, published in Jama Network Open and conducted by a Boston-based team, examined the estimated prevalence of the degenerative brain disease among NFL players who died from 2008 through 2023. Researchers found that the estimated rate of CTE among these players was substantially higher than the rates observed in brain samples collected from the general population.

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© Photograph: Stan Grossfeld/The Boston Globe via Getty Images

© Photograph: Stan Grossfeld/The Boston Globe via Getty Images

© Photograph: Stan Grossfeld/The Boston Globe via Getty Images

Research looked at prevalence of chronic traumatic encephalopathy in 2,362 players who died in 2008-2023

A new study published on Wednesday estimates that about 75% of former NFL players who died over a 15-year period had evidence of chronic traumatic encephalopathy (CTE).

The research, published in Jama Network Open and conducted by a Boston-based team, examined the estimated prevalence of the degenerative brain disease among NFL players who died from 2008 through 2023. Researchers found that the estimated rate of CTE among these players was substantially higher than the rates observed in brain samples collected from the general population.

Continue reading...

© Photograph: Stan Grossfeld/The Boston Globe via Getty Images

© Photograph: Stan Grossfeld/The Boston Globe via Getty Images

© Photograph: Stan Grossfeld/The Boston Globe via Getty Images

Jean Kaseya, of the Africa CDC, warns of the illness spreading like Covid unless more funding is secured to increase preparedness and possible treatment

The “unprecedented” spread of the Ebola outbreak means it could reach the UK and other countries, according to one of Africa’s top health officials.

As the current outbreak reached 10,000 cases, with almost 5,000 deaths, Dr Jean Kaseya, director general of the Africa Centres for Disease Control and Prevention (CDC), compared the outbreak to the Covid pandemic, which first took hold in China before spreading to countries across the world, claiming millions of lives, and ravaging health systems and economies.

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© Photograph: Sodiq Adelakun/Reuters

© Photograph: Sodiq Adelakun/Reuters

© Photograph: Sodiq Adelakun/Reuters

Jean Kaseya, of the Africa CDC, warns of the illness spreading like Covid unless more funding is secured to increase preparedness and possible treatment

The “unprecedented” spread of the Ebola outbreak means it could reach the UK and other countries, according to one of Africa’s top health officials.

As the current outbreak reached 10,000 cases, with almost 5,000 deaths, Dr Jean Kaseya, director general of the Africa Centres for Disease Control and Prevention (CDC), compared the outbreak to the Covid pandemic, which first took hold in China before spreading to countries across the world, claiming millions of lives, and ravaging health systems and economies.

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© Photograph: Sodiq Adelakun/Reuters

© Photograph: Sodiq Adelakun/Reuters

© Photograph: Sodiq Adelakun/Reuters

Привет, Хабр! Я Женя Горбач, продуктовый дизайнер в Альфа-Метрике, аналитическом продукте Альфа банка. Найти рефы для авторизации, оформления заказа или перевода — задача вполне понятная. Но что делать, если проектируешь сценарий, который редко встречается в других продуктах, а решения прямых конкурентов тебе не подходят?

Недавно я столкнулся именно с такой задачей во время редизайна одного из разделов нашего сервиса — каталога событий. 70% пользователей бросали загрузку событий, и нам предстояло выяснить, почему, и помочь им. Спойлер: более удобное решение получилось благодаря тому, что мы выпилили часть интерфейса. В этой статье расскажу, как с помощью ChatGPT, Deep Research и Mobbin через MCP я не только ускорил, но и качественно улучшил процесс поиска решения.

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Я изучаю посттренировочное квантование семейства RWKV-7 (от 0.1B до 13.3B параметров) двумя пресетами: REDUCTION (сжатие около 2.1x, почти без потерь) и COMPRESSION (около 3.1x, 4 бита на проекции). Исходный вопрос работы: почему 4-битный пресет на модели 2.9B деградирует сильнее, чем на 1.5B (+4.04% против +2.85% по перплексии), хотя ожидается обратное.

Оказалось, что до 86% вклада всей группы o_proj на 2.9B приходится на одну матрицу: выходную проекцию нулевого блока. Её вход несёт «массивный канал» (98% энергии входа в восьми каналах из 2560). Хранение этой одной матрицы в bf16 (0.5% файла) снижает KL к эталону на 39% и возвращает 2.9B в монотонную линейку; перевод эмбеддинга с 5 на 6 бит добавляет ещё −22% KL за 1.1% файла. Три естественные локальные метрики ошибки не предсказывают вред от квантования матрицы; предсказывает ошибка, внесённая в остаточный поток и умноженная на усиление ниже по глубине. На этом основании я строю автоподбор битности по правилу «снятый вред на байт» (−16…−39% KL при приросте файла не более 0.5%) и переношу GPTQ на ту же сетку (−29…−43% KL при тех же байтах).

Вместе методы дают потерю по перплексии от +2.76% (0.1B) до +0.70% (13.3B) на файле размером 31.6–35.2% от bf16, монотонно убывающую с размером модели. Пресет REDUCTION с GPTQ даёт +0.46…+0.07% при 46–50% от bf16. При равном размере файла KL моего 6-битного файла с GPTQ в 2.0–3.3 раза ниже, чем у GGUF Q6_K с imatrix, и в 3.5–7.4 раза ниже, чем у MLX int6; 4-битный файл в 2.1 раза точнее Q4_K_M на 1.5B, а Q4_K_M на 2.9B ломается. Отдельно описываю утечку калибровочного корпуса в мой первый оценочный набор и измеренный масштаб её влияния, а также разброс GPTQ между численно эквивалентными реализациями (около ±1.5% KL).

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Experts say symptoms such as dark circles under the eyes, grey skin, cracked lips and hair loss can be a warning sign – but there are other factors too

TikTok is rife with influencers warning of “ferritin face”, a term they use to describe the pallor, dark circles, dry skin, and hair loss claimed to indicate low iron stores. But is this based on fact or fiction, and when is it time to head to the GP?

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© Photograph: Alamy/PA

© Photograph: Alamy/PA

© Photograph: Alamy/PA

Experts say symptoms such as dark circles under the eyes, grey skin, cracked lips and hair loss can be a warning sign – but there are other factors too

TikTok is rife with influencers warning of “ferritin face”, a term they use to describe the pallor, dark circles, dry skin, and hair loss claimed to indicate low iron stores. But is this based on fact or fiction, and when is it time to head to the GP?

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© Photograph: AegeanBlue/Getty Images

© Photograph: AegeanBlue/Getty Images

© Photograph: AegeanBlue/Getty Images

Indonesia is battling its worst wildfires in more than a decade, made worse by El Niño. Many were deliberately set to clear land for farming, including palm oil plantations. More than 12,000 schools across Indonesia have closed because of the toxic haze. Natanael Undas, a school principal and photographer, has been documenting the fires on social media.

A prominent researcher claims to have a revolutionary approach to “interpretability,” or the science of why A.I. models do what they do. Other experts aren’t so sure.

The process included a gala featuring medical students doing aerial yoga and singing Taylor Swift to donors’ families. In some ways, it was absolutely perfect

When my mother, Erin O’Connell, was diagnosed with a rare and aggressive cancer in late 2022, one of her first thoughts was: “What will I do if I can’t work?”

At the time, she was 62 years old and working as a physical therapist in Portland, Oregon, where she had recently moved to live closer to me and my family. Reluctantly, she filed for short-term disability from her job and paused her training to become a volunteer search and rescue EMT.

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© Illustration: Ibrahim Rayintakath/The Guardian

© Illustration: Ibrahim Rayintakath/The Guardian

© Illustration: Ibrahim Rayintakath/The Guardian

It’s not impossible to spot the characteristics of a brewing financial crisis. We can look to 2008 for clues.

© Illustration by Andrei Cojocaru; photos by Getty Images

When actor Christina Applegate revealed that she had been misdiagnosed with multiple sclerosis, it triggered not only an outpouring of empathy for her, but raised important questions about how often people are told they have the condition when they don't. William Brangham discussed why MS can be so difficult to diagnose with Dr. Michael Kornberg of Johns Hopkins University.

Applegate revealed that despite the misdiagnosis, she still has "every symptom of someone with MS," adding, "I still have to use wheelchairs when I go to the doctor's office. I can't walk from the car to the room."

In the years after the 2010 BP oil spill, the number of fish in the deeper parts of the Gulf of Mexico dramatically declined.

Electric aviation is still in the very early stages of its development. But a number of companies are moving forward with more ambitious plans. In contrast to its approach with other forms of electric transportation, the Trump administration seems willing to embrace a bigger rollout. Aviation correspondent Miles O'Brien reports on the promise and the challenges of the budding industry.

Study reveals at least 2.3 million new cancer cases in 2024 were caused by common infections, almost all of which could have been prevented

A new study suggests elephants prepare their own treatments from plants known to have medicinal properties

It is hoped the factory-bred mosquitoes will be a long-term solution to the rapid spread of the disease-carrying insects